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54th Annual ESPE

Barcelona, Spain
01 Oct 2015 - 03 Oct 2015

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Barcelona, Spain; 1-3 October 2015 Further information

Plenary Lectures

Ontogeny of FGF21 in the human: Implications for metabolic health

hrp0084pl5 | Ontogeny of FGF21 in the human: Implications for metabolic health | ESPE2015

Ontogeny of FGF21 in the Human: Implications for Metabolic Health

Villarroya Francesc

Background: FGF21 is a hormonal factor with powerful anti-diabetic and anti-obesity properties in adults\. Studies in rodent models indicated that hepatic FGF21 expression and blood FGF21 levels are strongly induced after birth in response to fat provided by milk ingestion. Moreover, preliminary data indicate that FGF21 is present in maternal milk.Objective and hypotheses: Our objective is to determine, using human samples and pre-clinical experimental m...