ESPE Abstracts (2015) 84 P-3-637

About a Case of Basedow-Graves' Disease in a Infant

M A Bassaida, K Bourichea, D Senoucia, W Mazaria, F Hadj Kaddoura, F Ghellaia, A Bendjelloula, A Medjahdib, N Berberb & A S Bendeddouchea


aPediatrics, Faculty of Medicine and Hospital, Tlemcen, Algeria; bNuclear Medicine, Faculty of Medicine and Hospital, Tlemcen, Algeria


Background: A disease of the immune system, responsible for 95% of cases of hyperthyroidism in children is very rare at this age, it affects one child in 10 million.

Presentation: Khadija 3 year old girl admitted for goiter, no goitrogenic substances No drug Shot, No Inbreeding, goiter paternal aunt, The trouble was in the beginning 1 year a height and weight advance:+1 DS weight, height+3.2 DS, weakness, weight loss, Profuse sweating, tachycardia, irritability important, goiter, exophthalmos, cervical thyroid ultrasound increased size inhomogeneous echogenicity regular contours bilateral cervical lymphadenopathy. TSH: 0.05 uIU/ml, T4: 100pm/l, anti-TG Ab: 82 IU/ml, anti-TPO Ab: 926 IU/ml, anti-TRAK Ab: 32 U/l. the throide scintigraphic increased size uniform intense fixation, hyper goiter capturing evoking Basedow’disease autoimmune diseases négatif. She is put under Propranolol, eye protection and Carbimazole 0.5 mg/kg per day for 3 months regression goiter, exophthalmos, T4: 28 pmol/l, anti-TRAK Ab: 23 U/l.

Conclusion: Need for improvements in the therapeutic management with identification of prognostic factors for disease remission, which could help to better define the optimum period of medical treatment and guide when choosing radical treatment when it will be necessary.

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