ESPE2016 Poster Presentations Diabetes P1 (72 abstracts)
The Relationship between the Serum Irisin Levels and the Metabolic Control in adolescents with Type 1 Diabetes
Aysegul Yuksel , Gulcan Seymen Karabulut , Canan Baydemir , Gul Yesiltepe Mutlu , Serkan Isgoren , Mustafa Cekmen & Sukru Hatun
Pediatric Endocrinology and Diabetes, Faculty of Medicine, Clinic/Kocaeli University, Kocaeli, Turkey
Background: Irisin is an adipomyokine secreted by many tissues. Because it has known relationships with the energy metabolism and exercise, its relationships with obesity and type 2 diabetes (T2D) are being focused on. Its relationship with type 1 diabetes (T1D) is unknown.
Objective and hypotheses: In this study, the relationships between the serum irisin level and the metabolic control were investigated in adolescents with T1D.
Method: The study group consisted of 125 T1D patients with diabetes duration of at least 2 years, 57 obese and 44 non-obese children, all were aged between 10 and 18 years. The metabolic parameters, anthropometric characteristics and body fat distributions and z-scores (by DXA) were measured and relationships of these with the serum irisin levels were examined.
Results: When all subjects were evaluated together, irisin levels were 3.08 (2.54–3.54) mcg/ml in girls and 3.12 (2.52–3.46) mcg/ml in boys, and no significant difference was found according to gender (P>0.05). When the serum irisin levels of the T1D, obese and normal patient groups (3.20 (2.78–3.66), 3.08 (2.46–3.42) and 2.60 (2.17–3.19) mcg/ml respectively) were analyzed, irisin levels in the diabetic group were found to be significantly higher (P<0.001).
Conclusion: Serum irisin levels of T1D adolescents were higher than the group consisting of obese and non-obese individuals.
Article tools
My recent searches
My recently viewed abstracts
ESPE Abstracts
© Bioscientifica 2024 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more