ESPE Abstracts (2016) 86 P-P1-257

Health-Related Quality of Life and its Associated Factors in Children With Type 1 Diabetes Mellitus

Marta Murillo-Vallesa,b, Luis Rajmilc,d, Joan Bel-Comosa, Jacobo Pereze, Raquel Corripioe, Gemma Carrerasf, Xavier Herrerog, Jose-Maria Mengibarg, Dolors Rodriguez-Arjonac, Ulrike Ravens-Siebererh & Hein Raati


aUniversity Hospital Germans Trias i Pujol, Badalona, Barcelona, Spain; bAutonomous University of Barcelona, Barcelona, Spain; cCatalan Agency for Health Quality and Assessment, Barcelona, Spain; dIMIM (Hospital del Mar Institute of Medical Research, Barcelona, Spain; eHospital of Sabadell, Corporació Sanitària Parc Taulí, Sabadell, Barcelona, Spain; fHospital Sant Pau, Barcelona, Spain; gCorporació de Salut del Maresme i la Selva, Barcelona, Spain; hUniversity Medical Center Hamburg-Eppendorf, Hamburg, Germany; iUniversity Medical Center Rotterdam, Rotterdam, The Netherlands


Objective: To assess health-related quality of life (HRQOL) in a cohort of children and adolescents with type 1 Diabetes (T1DM) and its associated factors.

Methods: This was a descriptive study of 136 patients with T1DM from five hospitals in Catalonia, Spain (72 girls, mean age 13.4 years (range 8–19). Inclusion criteria were more than 6 months from diagnosis, more than 8 years old and without cognitive problems. Sociodemographic (age, sex, family level of education, type of family and origin) and clinical variables (type of insulin therapy, duration of disease, adherence to treatment, BMI and HbA1c) were collected. HRQOL was assessed using the EuroQol-5D (EQ-5D-Y) and KIDSCREEN, collected via web. Mental health status was assessed using the Strengths and Difficulties Questionnaire.

Results: Physical-well-being mean scores were lower (worse) than the European average (<50) and especially in girls, older children (>11 years old), those from single-parent families, and those with low adherence. Older children and patients with poor metabolic control (HbA1c >7.5% (58 mmol/mol)) showed worse scores in the KIDSCREEN-10 index. Similar results were observed with the EQ-5D-Y. HRQOL showed negative correlation with age, HbA1c, and mental health. Multivariate models showed that age, single-parent families, adherence and mental health were the most influential factors.

Conclusions: Diabetic patients report similar HRQOL than the population of the same age with slightly worse physical well-being. The study shows some factors to be taken into account to improve HRQOL, and also the feasibility of using web to collect information in clinical practice.