ESPE Abstracts (2016) 86 P-P2-321

Achievement of Metabolic Parameter Goals in Children and Adolescent with Type 1 Diabetes According to the Latest ADA/ISPAD Standards of Medical Care in Diabetes in a Pediatric Diabetes Clinic in North Greece

Maria Papagianni, Anastasios Vamvakis, Kiriaki Tsiroukidou, Konstantina Kosta, Iliana Mameka, Christos Chatzakis, Efthimia Grenda & Ioannis Tsanakas


Endocrine Unit, 3rd Pediatric Department, Aristotle University of Thessaloniki, Hippokrateion Hospital of Thessaloniki, Thessaloniki, Greece


Background: Blood glucose control in children and adolescents with type 1 diabetes (TD1) is the most important goal in order to reduce potential complications. Following up these patients frequently and recording the relative metabolic parameters on a regular basis is necessary.

Objective and hypotheses: The aim of the study was to compare the level of metabolic control in the children and adolescents with TD1 that are followed up in our Pediatric Diabetes Clinic with the targets set by the latest ADA/ISPAD Standards of Medical Care in Diabetes.

Method: Seventy-four children and adolescents (38 boys, 36 girls), aged 12.6±3.9 years old, suffered from TD1 for 5.8±4.1 years, met the criteria (<18 years old, >1 year from TD1 diagnosis, >3 visits per year) for participating in the study. 61% of the patients had normal weight, 25% were overweight and 14% obese. Fifty of the patients were under multiple insulin injections and 24 on insulin pump. For all patients metabolic parameters (HbA1c, BMI, Blood Pressure, LDL, HDL, Triglycerides) were recorded and they compared with the goals set by ADA (HbA1c<7.5%, LDL <100 mg/d, HDL>35 mg/dl, TG<150 mg/dl, BMI<85th centile, BP<90th centile).

Results: In total, 62% of patients achieved HbA1c target (7.4±0.8). There was no difference between patients on multiple insulin injections or insulin pump (7.3±0.8 vs 7.4±0.9, respectively). When the patients were categorized by age (<12 and >12 years old), it was found that 65% of the patients over 12 years old and 54% of those below 12 years old had HbA1c<7.5%. Lipid profile targets for HDL (58±15 mg/dl), LDL (98±28 mg/dl), TG (70±33 mg/dl), were achieved by 97, 54, 97% of all patients respectively. In total, 97% of the patients had normal BP.

Conclusion: Regular monitoring (at least three visits per year) of TD1 patients can lead to a better glucose control, thus reducing the potential for future health complications.