ESPE Abstracts (2018) 89 P-P3-073

Effects of Diabetes Mellitus Type-1 on Vitamin D Status Among Children

Abeer Alshareef


Ministry of Health, Jeddah, Saudi Arabia


Introduction: Vitamin D defciency is a common health concern among all children world wide.together with the rapidly increased prevalence of diabetes mellitus\.This study was conducted to determine if diabetes is associated with increased risk of vitamin D deficiencydy examination the influences of diabetes effecting status on specific patients disease characteristics in regards to vitamin D level among children from saudi arabia.

Methods: All retrospective and prospective patients with proven diagnosis of type-1-diabetes following up at pediatric endocrinology clinic between Jan 2016–Dec 2017\.. the participants about 100 diabetic patients age 2–14 years were enrolled in the study including the age–sex–duration of the disease, symptoms and signs of vitamin D deficiency. Blood samples were collected, 25 (OH) vitamin D together with glycosylated hemoglobin AIC level measured by high performance liquid chromatography standardized to the Dcct assay.

Results

We divided the children into three groups according to 25(OH) vitamin D level.

(1) deficiency, 25(OH) vitamin D more or equal 20 ng/ml\..

(2) insufficiency, 25 (OH) vitamin D between 20–29 ng/ml\..

(3) sufficiency, 25(OH) less or equal 30 ng/ml\..

The outcome of the study shows that about 60 patients belong to group (1)\.. 25 patients belong to group (2) and 15 patients belong to group (3)\..in addition to that patients belonging to group (1) have higher HbAIC in comparison to group (2) and (3)\..also patients with longer duration of Diabetes are more liable to have vitamin D defieciency in comparison to the newly diagnosed\.

Conclusions: Type–1 Diabetes is associated with an increased risk of vitamin D deficiency. Patients with type 1 Diabetes sustained some what disproportional relation between the control of Diabetes reflected by HbAIC and vitamin D. Duration of diabetes type 1-has a negative impact on vitamin D adequacy. These finding have an important health implication given the increasing prevalence of type 1 Diabetes and the morbidity and mortality associated with vitamin D inadequacy. Ensuring vitamin D sufficiency throughout childhood and adolescence in this population seems especially warranted.

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