Background: This study aims to describe the predictive factors of severe obesity in children followed in French Guiana.
Methods: In this observational study, the patients from the French Guianese Childhood Obesity Group database were prospectively included, after giving a statement of patients non opposition.
Results: Our group classifications revealed that 36 of 150 (24%) participants were classified as being Metabolically Unhealthy obesity (MUO), while 114 of 150 (76%) were categorized as metabolically healthy obesity (MHO). MUO-patients were older. Their mothers had more severe obesity. We also observed that their systolic blood pressure was higher. The median Z-score BMI of children with MUO was 4, 9 [4, 055, 38], which shows a more obese condition than the MHO group. The median waist-to-height ratio (WTHR) of our study population was high, either 0.63 [0.540.59]. No significant differences in the term of pregnancy, fathers obesity, gender, birth weight, feeding, diastolic blood pressure and WTHR were found between the two groups. The predictors of MUO status, after adjusting for age and sex, were mothers obesity and high childs waist circumference. Among the comorbidity, there were two Down syndrome, one Cornelia de Lange syndrome, one Nephrotic Syndrome and one Epilepsy. The leptin hormone and insulin levels were higher in MUO than in MHO, while 25-OH D-vitamin was higher in MHO.
Conclusion: This study indicates the need to incorporate waist circumference into routine clinical practice, in addition to traditional measures of weight, height, body mass index and waist-to-height ratio.
Keywords: Mothers obesity, waist circumference, predictive factors, childhood obesity, observational Study, French Guiana.
27 - 29 Sep 2018
European Society for Paediatric Endocrinology