ESPE Abstracts (2018) 89 P-P3-257

Growth Response in Noonan Syndrome in Indian Children

Smita Ramachandran, Aashish Sethi & Inderpal Kochar


Indraprastha Apollo Hospital, Delhi, India


Objective: To evaluate the growth response in children with Noonan syndrome (NS) treated with growth hormone (rGH).

Methods: We retrospectively collected data from 2007 of pre-pubertal children with NS, their baseline auxological parameters were recorded pre and post treatment.

Results: A total 1134 were treated with growth hormone for short stature of which there were six cases of NS, constituting 0.5% of the short stature. There were three males and one females, mean age of presentation was 10.8yrs +1.78. The mean height at the start of treatment was 128.75 cm and improved to 138.13 cm after 12 months of rGH. The average height velocity was 9.38 cm/year.

Conclusion: The prevalence of NS is very limited in Indian population but timely diagnosis and treatment can result in improved final height.

Article tools

My recent searches

No recent searches.

My recently viewed abstracts