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58th Annual ESPE

Vienna, Austria
19 Sep 2019 - 21 Sep 2019

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The theme of this year’s meeting is Variety and Variation in Paediatric Endocrinology. Join us in Vienna to explore the diversity we encounter in our discipline and the care that we have to exercise when using the term “normality”. Whilst gaining an update on the latest treatments, clinical best practice and cutting edge research in the field of paediatric endocrinology.

Symposia

Novel Insights in Our Understanding of Disorders of Sex Development: From Genes to Clinical Outcomes

hrp0092s3.3 | Novel Insights in Our Understanding of Disorders of Sex Development: From Genes to Clinical Outcomes | ESPE2019

Novel Insights into Sex Determination: Mutual Antagonism of Pro-Testis and Pro-Ovary Signalling Pathways

Greenfield Andy

There is no single conception of sex that covers the multitude of biological process that are commonly encompassed by the term and its cognates. Gonadal sex determination is sometimes known as 'primary' sex determination due to its centrality in our understanding of 'maleness' and 'femaleness'. In mammals, this is characterised by the sexually dimorphic development of an initially bipotential gonadal primordium in the fetus into either a testis or an ov...