ESPE2019 Poster Category 3 Late Breaking Abstracts (69 abstracts)
Body Mass Index and Incident Type 1 Diabetes in Children from Lesser Poland Over an 11 Year Observation Period
Barbara Wasyl-Nawrot 1 , Małgorzata Wójcik 2 , Joanna Nazim 2 , Jan Skupień 3 & Jerzy Starzyk 2
1Department of Pediatrics, Hospital in Brzesko, Brzesko, Poland. 2Department of Pediatric and Adolescent Endocrinology, Chair of Pediatrics, Pediatric Institute, Jagiellonian University, Medical College, Kraków, Poland. 3Department of Metabolic Diseases, Jagiellonian University Medical College, Kraków, Poland
Background: One of the speculated causes of the decreasing age of onset of type 1 diabetes is the increase in body weight in children. This so-called accelerator hypothesis is, however, controversial. The aim of the study was to test whether younger age of type 1 diabetes onset is associated with higher BMI-SDS at the time of diagnosis.
Methods: Retrospective data analysis from medical records of all patients under the age of 14 (n=559; 50.6% male), with newly diagnosed type 1 diabetes in Lesser Poland between 2006 and 2017.
Results: There were only 15 (2.7%) cases of obesity at the moment of diagnosis. An increase in BMI-SDS by 1 unit was associated with the development of the disease 0.54 years later. Interestingly, BMI-SDS was higher in the older age groups, during puberty.
Conclusion: The results of the present study do not confirm that younger age of type 1 diabetes onset is associated with higher BMI-SDS at the time of diagnosis, and therefore are insufficient to prove the accelerator hypothesis. However, the results point to a possible contribution of increased body weight during puberty on the age of type 1 diabetes manifestation. This concept requires further investigation.
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