ESPE Abstracts (2019) 92 P1-272

Age at Menarche Over the Last Decades and Inter-Regional Variability in Northern Spain

Pablo Alonso Rubio1, Lucía Fernández González2, Cecilia Arbesú Saracho2, José Ignacio Pérez Candás3, Isolina Riaño-Galán1,2,4


1Pediatric Endocrinology. Hospital Universitario Central de Asturias, Oviedo, Spain. 2University of Oviedo, Oviedo, Spain. 3Pediatrics Sabugo´s health center, Avilés, Spain. 4Spanish Consortium for Research on Epidemiology and Public Health (CIBERESP). Instituto de Salud Carlos III, Madrid, Spain


Introduction: Menarche is the time of first menstrual bleed and it occurs, on average, 2 to 2.5 years after the onset of puberty. Globally, the age of menarche had been reduced since the last century.

Objective: To examine the evolution of the age of menarche over the last decades and inter-regional variability in an autonomous community located in northern Spain which is divided in eight health areas.

These health areas differ between them from predominance of rural or urban environments.

Material and Methods: A retrospective, descriptive studio was made. We revised the age of menarche of girls and teenagers born between 1920 and 2008, in the eight health areas. These data were collected from clinical records and electronic medical history from ninety public primary health centers of all health areas of the region.

We did two analysis. First, birth decade was compared with age at menarche. Second in the teenagers born between 1998 and 2008, the age of menarche was compared with the health area to which they belonged.

Results:

Table 1: Birth decade vs age at menarche
Age at menarche (years)
Birth decadeMeanMedianModeDSN
1920-192914.2914141.9291
1930-193913.9414141.96540
1940-194913.1813141.73594
1950-195912.7713131.546183
1960-196912.7513131.544791P<0,05
1970-197912.7813131.513196
1980-198912.6213121.5416590
1990-199911.8412121.0613126
2000-201011.6412120.910375

The second analysis showed differences in the mean age at menarche by health area, ranged between 11.78 (0.87) years in the most rural area to 11.55 (0.92) years in the most industrialized area (P<0,05).

Conclusions: • The average menarcheal age decreased through the last decades. It is probably due to both genetic and environmental factors.

• The differences found in the mean age of menarche by belonging health area were statistically significant but maybe they aren't clinically significant. In order to know the influence of environmental factors over the onset of the menarche, a more detailed study should be performed.

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