ESPE Abstracts (2019) 92 P2-291

Investigation of Oxidative Effect in Saliva and Gingival Groove Fluids in Children with Hashimoto Thyroiditis

Müge Atar1, Aykut Tan1, Zuhal Yetkin Ay1, Müge Atar2, Özgür Pirgon1


1Suleyman Demirel University, Isparta, Turkey. 2Kocaeli Derince eğitim ve Araştirma Hastanesi, Kocaeli, Turkey


The aim of this study was to determine the periodontal health status in patients with Hashimoto thyroiditis (HT) and investigate the gingival groove fluid and saline oxidative stress parameters in order to demonstrate their relationship.

Method: 30 patients between the ages of 11-17 years and 30 healthy volunteers aged between 10-17 years were included in the study. Serum tT4, TSH, anti-TPO, glucose, insulin, ALT, triglyceride, total cholesterol, HDL and LDL cholesterol, ACTH, cortisol and calcium levels were determined in all of the adolescents included in the study. Pocket depth, gingival index, plaque index, presence or absence of hemorrhage during probing was interpreted for periodontal examination.

Results: Gingival groove fluid and saliva total oxidant level levels and salivary oxidative stress index (OSI) were higher in the patient group but no statistically significant difference was found. No statistically significant difference was observed between the groups for periodontal parameters and oxidative stress parameters.

Conclusion: Although the OSI levels in the saliva and gingival cavity were high in the patient group, no statistically significant difference was found. We concluded that periodontal injury process has started and that the process which is continuing in the pathogenesis would end with periodontal disease.

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