ESPE Abstracts (2019) 92 P3-263

Papillary Thyroid Cancer in Children: Single Center Results

Nihal Hatipoğlu1, Gül Direk1, Zeynep Uzan Tatli1, Ülkü Gül Şiraz2, Dilek Çiçek1, Ebru Gök1, Emre Sarikaya1, Mustafa Kendirci1, Selim Kurtoğlu3


1Erciyes University Faculty of Medicine Department od Pediatric Endocrinology, Kayseri, Turkey. 2Van Training and Research Hospital, Van, Turkey. 3Memorial Hospital Department of Pediatric Endocrinology, Kayseri, Turkey


Introduction: Thyroid cancers are rare cancers in children and their incidence is 1.4% in pediatric malignancies. However, its frequency is increasing. While the incidence of prepubertal children is equal among girls boys, it increases with age in female patients. Radiotherapy, which is applied to the neck region, and hashimoto disease are the risk factors. The relationship between Hashimoto's disease and papillary thyroid cancer is thought to be associated with chronic inflammation. The prognosis is very good when appropriate treatment is applied. Most patients are diagnosed with thyroid nodules or neck lymph nodes. Thyroid ultrasound, fine needle aspiration biopsy and diagnostic hemithyroidectomy are performed. Treatment of total thyroidectomy and lymph node dissection recommended for each patient in recent years. In the presence of lymph node and distant metastases, postoperative iodine 131 is recommended.

The clinical and pathologic features and prognosis of patients with papillary thyroid cancer were analyzed retrospectively.

Cases: The data of 19 patients diagnosed in our clinic were evaluated retrospectively. 14 of the patients were female and 5 of them were male and the mean age at diagnosis was 13.6. The most common complaint was neck swelling. Most patients had neck lymphadenopathy at the time of diagnosis. Five of the patients were diagnosed with thyroid nodules on the basis of hashimoto. In the examination of these patients, nodules were not detected and nodules were detected in the ultrasound examination. When we look at the distribution according to years, it was seen that the number of patients diagnosed with hashimoto increased. The pathology of all patients was consistent with papillary thyroid cancer. All of the patients were operated, except 2, all of them received radioactive iodine treatment after the operation.

Result: In recent years, the incidence of thyroid papillary cancer has increased. In addition, it has been observed that patients diagnosed with hashimoto have also increased in patients diagnosed in recent years. Therefore, we would like to emphasize the importance of performing an annual ultrasound scan of hashimoto thyroiditis.

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