ESPE Abstracts (2019) 92 P3-316

Epidemiological and Socioeconomic CHANGES in the Child Population from Debut DM1 in this 21st Century

Ignacio Diez-Lopez1,2, Ainhoa Sarasua-Miranda1, Maria Isabel Lorente-Blazquez1


1HU Araba-Peadiatric Endocrinology, Vitoria, Spain. 2Basque Country University - UPV, Vitoria, Spain


Objectives: To demographic, socio-economic and social changes in the population of children who debuted in this century with DM type 1a

Patients and Methods: Study patients with Type 1 Diabetes Mellitus from January 2000 to the present. Longitudinal study of global epidemiological, social, demographic and clinical variables and by five-year periods, focusing on the latte at Basque Country

Results: 105 patients (34% M / 66% H), with age at diagnosis of 8.7 ± 3.1 years (43% with ketoacidosis vs 57% without ketoacidosis), HbA1c average to debut of 10.9 +

The incidence declared in Euskadi is 12.9 cases / 10 5

57% are families of Spanish origin, 43% at least one parent is a foreigner. If we value the last five-year period, the proportions are 28% foreign vs. 72% foreign. The rate of foreigners <15 years in Euskadi is 8.2%, Alava 16.8%. The OR of children with DM type 1 debut is 2.55 globally (p: 0.001) and in the last five years of 4.20 (p: 0.0001). If we value this sub-population, the degree of CAD is 70% (OR 2.5 p.001 vs foreign), HbA1c average of 11.5%, a duration of symptoms of 4.8 weeks (OR 2.5 p.001 versus outsiders), 100% autoimmunity, 15% other autoimmune. 16% of families at debut had a "non-classical" family unit (separation, divorce, single parents). Similar to average family data with children in Euskadi 18%. At the end of the study and after several years of debut (average 5.8 years) the rate was increased to 28%. OR 1.80. If we study the sub-group of foreign population (43 families, 2 at debut (5% p: 0.01 with respect to outsiders)) they were in this situation. After the study, this subgroup had not modified the rate.

Conclusions: We assume that this study may have some deficiencies due to the regionalization of the sample, but demonstrates a real social change in our population with an impact on diabetic pathology. There is a more vulnerable population (by genetics, culture, customs), which in turn is increasingly numerous: the immigrant; who comes later to consult Debuts e most prevalent clinical situation worse (CAD). The barriers and language and cultural differences are added handicap in monitoring these patients. On the other hand, the debut of a child can be a cause of serious family breakdown, as evidenced by the increase in the separation rate. This makes us suggest recommending an increase in emotional support for these families

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