ESPE Abstracts (2019) 92 P3-86

Clinical Profile of Paediatric Patients with type 1 Diabetes Mellitus at a Tertiary Health Care Center in the Oriental Region of Northeastern Morocco

Salma Ben Yakhlef, Nada Derkaoui, Siham Rouf, Amine Ezzerrouqi, Hanane Latrech


Oujda's Mohammed VI university hospital, Oujda, Morocco


Introduction: The growing pandemic of type 1 diabetes is considered as an enormous multifactorial public health challenge in the world. Many targeted interventions should be provided to improve type 1 diabetes management especially during childhood and adolescence.

The purpose of this study is to elucidate the epidemiological, clinical and management profile of type 1 diabetes in Moroccan children and adolescents followed up in the endocrinology department of Oujda's Mohammed VI university hospital.

Material and Methods: This is a retrospective data analysis of children and adolescents with type 1 diabetes followed up in in the endocrinology department of Oujda's Mohammed VI university hospital.

Results: 83 children and adolescents with type 1 diabetes were involved in the study. The number of patients diagnosed with type 1 diabetes was higher during the cooler months of the year compared to the warmer ones, and a positive family history in first-degree relatives was reported in 23% of patients.

The overall mean age at diagnosis was 12,8 years and the most commonly reported presenting symptoms were polyuria (85%), polydipsia (82%), and weight loss (63%)

Diabetic ketoacidosis at initial presentation was diagnosed in 40% of patients and 34% of cases were admitted for unstable glycaemic control ; with an average of initial hemoglobin A1c value of 12,3 %.

The classic b-cell autoimmune markers were surveyed in 57% of cases ; and 67% were found positive for antiglutamic acid decarboxylase antibodies (GADA).

All the included patients were screened for co-occurring autoimmune disorders ; and hypothyroidism was detected in 13% and coeliac disease in 9,1% of cases.

Chronic degenerative complications were noticed in 15% of patients with retinopathy in 10,4% and diabetic kidney disease in 7,2%.

Basal Bolus insulin regimen was adopted in 95,7% and 48,3% of patients were enrolled in flexible insulin therapy training programmes. Insulin pumps were used in 14% of cases.

Conclusion: Endocrinology department of Oujda's Mohammed VI university hospital offers a personalized healthcare, for each child or adolescent with type 1 diabetes in order to improve metabolic control, decrease the risk of hypoglycemia and enhance the quality of life

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