hrp0098p2-95 | Fat, Metabolism and Obesity | ESPE2024

The Effect of Vitamin D Supplementation on Fatty Liver Disease and Insulin Resistance

Anil Korkmaz Huseyin , Barisik Vatan , Atila Dincer , Cekdemir Yasin

Background: Vitamin D deficiency has been shown to increase fatty liver disease (FLD) incidence in patients with obesity (4,5). This study aim ed to determine the effects of a single dose of 300,000 IU cholecalciferol on insulin resistance and fatty liver disease (FLD) in children with obesity with vitamin D deficiency.Methods: In this clinical study, 128 patients aged 8-18 years with obesity and vitamin D deficiency wer...

hrp0089p2-p123 | Fat, Metabolism and Obesity P2 | ESPE2018

Allopurinol Ameliorates Non-Alcoholic Fatty Liver Disease in Rats

Anil Korkmaz Huseyin , Aktug Huseyin , Atila Dincer , Barisik Vatan , Arslan Nur , Erbas Oytun

Background: Hyperuricemia has been found to be associated with non-alcoholic fatty liver disease (NAFLD).Aim: The aim of this study was to evaluate whether allopurinol affects the course of experimental NAFLD in rats.Study Design: Mature, albino Sprague Dawley rats were fed water containing 30% fructose without ethanol for up to 8 weeks. After demonstration of steatosis in the 8th week, either allopurinol or saline was administered...

hrp0097p1-448 | Fat, Metabolism and Obesity | ESPE2023

The Association between Vitamin D deficiency and Hepatosteatosis in Obese Children and Adolescents. (Underreview in Hormone Research Journal- HRP-2023-1-19)

Anil Korkmaz Huseyin , Bhushan Arya Ved , Barisik Vatan , Atila Dincer , Coskunol Fulya , Alci Serra , Ertug Cekdemir Yasin , Torlak Derun , Ozkan Behzat

Objective: To compare the serum 25-hydroxy Vitamin D [25(OH)D] concentrations in children and adolescents with obesity with and without hepatosteatosis, and investigate the relationship between serum 25(OH)D concentrations and severity of hepatosteatosis. We also aimed to assess the effect of vitamin D treatment after 6 months on hepatosteatosis and liver biochemistry.Methods: One hundred thirty-three obese patients with...