hrp0086p1-p235 | Diabetes P1 | ESPE2016
Elkaffas Rasha
, Musa Noha
, Franco Elisa De
, Madani Hanan A
, Shaalan Yomna
, El-Kaffas Rania M.H.
, Hassan Mona
, Hafez Mona
, Kholi Badawy El
, Flanagan Sarah E
, Ellard Sian
, Hussain Khalid
Background: Neonatal Diabetes Mellitus (NDM) is a rare form of monogenic diabetes that typically presents during the first 6 months of life. Its prevalence is about 1:100 000 live births; however it may rise up to 1:29 000 in highly consanguineous populations. Mutations in 22 different genes are reported; with the most common cause being potassium channel subunit gene (KCNJ11/ABCC8) mutations. However, causative mutations among consanguineous populations seem to diffe...