hrp0086fc1.3 | Adrenals | ESPE2016

Steroidogenesis in the Human Fetal Adrenals at the End of the First Trimester

Savchuk Iuliia , Morvan M.L. , Soeborg T. , Antignac J.P. , Danielsson K. Gemzell , Bizec B. Le , Soder O. , Svechnikov K.

Background: Steroid hormones produced by the human fetal adrenals (HFA) are suggested to regulate intrauterine homeostasis and the maturation of certain fetal organs necessary for extrauterine life. Appropriate development and hormonal function of the HFA therefore are critical for normal fetal maturation and survival. Little is known about the possible relationship between the expression of steroidogenic enzymes and corresponding transcription factors in the HFA in vivo</...