ESPE2014 Poster Presentations Fat Metabolism & Obesity (1) (12 abstracts)
Prenatal Maternal Weight and Weight Status and Lipid Profile of the Offspring
Isolina Riaño-Galan a , Cristina Rodriguez-Dehli a , Ines Olaya Velázquez a , Ana Fernández-Somoano b , Damaskini Valvi c , Marisa Rebagliato d , Jesus Ibarluzea e & Adonina Tardon b
aHospital San Agustín Pediatria, Aviles, Spain; bCIBERESP and Oviedo University, Preventive Medicine, Oviedo, Spain; cCIBERESP and Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain; dCIBERESP and Unit of Environment and Health, Centre for Public Health Research (CSISP/FISABIO), Valencia, Spain; eCIBERESP and BioDonostia Health Research Institute, Donostia, Spain
Background: Childhood obesity is a serious public health concern. To identify risk for obesity in early childhood is important.
Objective: To analyse association of pre-pregnancy maternal weight with BMI and metabolic profile at 4 years.
Methods: 2604 pregnant mothers and 1960 children from the Spanish population-based cohort study Environment and Childhood (INfancia y Medio Ambiente) Project (INMA). Research protocol was approved by the Ethics Committee. We analysed maternal BMI, gestational weight gain (GWG), BMI at 4 years and prevalence of overweight (OW) and obesity (OB) according to IOTF. Lipid profile was determined in a subgroup of children.
Results: 4.6% mothers were underweight (BMI <18.5 kg/m2), 68.8% normal (BMI 18.5–24.9 kg/m2), 18.7% had OW (BMI 25–29.9 kg/m2) and 7.9% OB (BMI ≥30 kg/m2). GWG was as recommended in 37.9% pregnant mothers, low in 24.2% and high in 37.9%. 20.2% children had OW or OB at 4 years. There are positive association between pre-pregnancy BMI and BMI at 4 years (P-trend <0.001). Maternal pre-pregnancy OW/OB increases the risk of child OW/OB by 1.3 (95% CI: 1.2–1.4). Table 1 shows lipid profile at 4 years (mean (S.D.)).
| Normal weight (n=413) | Overweight (n=70) | Obese (n=35) | P (trend) | |
| Total cholesterol (mg/dl) | 163.9 (27.2) | 168.1 (24.9) | 171.9 (24.8) | 0.050 |
| C-HDL (mg/dl) | 54.5 (12.2) | 51.4 (11.2) | 51.9 (9.2) | 0.042 |
| Triglycerides (mg/dl) | 78.9 (40.4) | 85.8 (42.2) | 98.5 (52.2) | 0.005 |
Conclusions: High prevalence of OW/OB maternal and at 4 years was detected. Correlation between them was found. An adverse metabolic profile is associated with overweight and obesity in 4 years-old children. Childhood obesity prevention must be started from pregnancy and infancy. Global cardiovascular risk prevention program focused on obesity prevention must be applied early in life. Table 1
Volume 82
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