ESPE Abstracts

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In this presentation, we will highlight areas of progress in pediatric brown adipose tissue (BAT) research over the past decade, including the general acceptance that this tissue is much more prevalent in children than adults and in infants than in children. Available longitudinal data in pediatric patients provide strong evidence in support of an inverse association between BAT activity and white adipose tissue (WAT) accumulation, most strikingly in the intra-abdominal depot....

Lipodystrophic syndromes are rare and heterogeneous diseases, characterized by a generalized or partial loss of adipose tissue (lipoatrophy) associated with metabolic complications usually associated with obesity: insulin-resistant diabetes, dyslipidemia, ovarian hyperandrogenism and non-alcoholic fatty liver disease.Molecular genetic studies in different types of lipodystrophies showed that primary adipocyte alterations leading to impaired adipogenesis ...