ESPE Abstracts (2019) 92 P3-72

Hematologic Indices Indicating Platelets Activity in Children with Type 1 Diabetes

Setila Dalili, Adel Baghersalimi, Shahin Koohmanaee, Afagh Hassanzadeh Rad, Venus Farzamfard

Pediatric Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran, Islamic Republic of

Aim: The aim of this study was to evaluate hematological indices especially PLT indices in children with T1DM

Materials and Methods: in this case-control study which was conducted on 166 participants including 83 children with diabetes type 1 and 83 children hospitalized for thorough assessment of short stature, PLT count, MPV, PDW, WBC count, hemoglobin, blood sugar,PCT, P-LCR, ans PLR were assessed. Patients with type 1 diabetes were divided into 2 groups including good and poor control based on HbA1c level below and above 7.5, respectively.

Results: Results showed positive correlation between age, hemoglobin, blood sugar, PCT, PLR, and HbA1c in children with diabetes. The area under the curve for PCT was 0.811 (0.663-0.959) and the cut-off point of PCT was 0.19. results indicated that only raised PCT (>0.19) was related with poor metabolic control and can put the patients to the risk of future cardiovascular events.

Conclusion: multiple PLT parameters, and a scoring system for them in patients with type 1 diabetes mellitus can be recommended

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