ESPE Abstracts (2021) 94 P1-94

ESPE2021 ePoster Category 1 Thyroid A (10 abstracts)

Evaluation of children with intrathyroidal ectopic thymus

Emine Ayça Cimbek 1 , Serpil Kaya 2 , İlker Eyüboğlu 3 , Hasan inç 3 & Gülay Karagüzel 1

1Department of Pediatric Endocrinology, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey; 2Department of Pediatrics, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey; 3Department of Radiology, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey

Background: Intrathyroidal ectopic thymus (IET), a benign lesion due to aberrant thymic migration during embryogenesis, is often discovered incidentally. Most of the reports in the literature describe individual cases or small series. We aimed to present the ultrasound (US) features, diagnostic methods, and follow-up of IET in children and adolescents.

Methods: We searched our database of patients under 18 years old with a nodular thyroid lesion detected by US, between January 2007 and December 2019. In 30/255 (11.7%), IET was diagnosed.

Results: The study included these 30 patients (20 males/10 females), mean age 5 years (0.1-12.2, median 5.6) with 34 lesions diagnosed by US as ’incidentalomas’. None of the patients had palpable nodules. On US, IET appeared as a hypoechoic lesion, with multiple punctuate internal echoes. 29/34 of lesions had well-defined margins. The most common location of IET was in the middle part (27/34) of the left lob (19/34). The mean longest diameter at diagnosis was 6.4 (2.5–21, median 4.5) mm. Sonographic follow-up was available in 25 patients with 27 lesions. The mean time of observation was 2.7 (0.3-7.5, median 2.1) years. While 13/27 cases showed decreased size or regression during follow-up, the other 13 increased in size, and there was no change in size in one. Fine needle aspiration (FNA) was performed in 5 patients and surgery in one.

Discussion: IET should be considered in the differential diagnosis of pediatric thyroid nodules as a cause of FNA and/or surgery. Regular US monitoring can be used safely in the follow-up of this lesion.

Volume 94

59th Annual ESPE (ESPE 2021 Online)

22 Sep 2021 - 26 Sep 2021

European Society for Paediatric Endocrinology 

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