ESPE2021 ePoster Category 2 Multisystem endocrine disorders (13 abstracts)
Thermoregulatory delays in Greek PCOS adolescents
Styliani Geronikolou 1,2 , George Chrousos 1,2 , Dennia Cokkinos 2 & Flora Bacopoulou 1
11Center for Adolescent Medicine and UNESCO Chair on Adolescent Health Care, First Department of Pediatrics, School of Medicine, National and Kapodistrian University of Athens, “Aghia Sophia” Children’s Hospital, Athens, Greece; 22Clinical, Translational and Experimental Surgery Research Centre, Biomedical Research Foundation of Academy of Athens, Athens, Greece
In this case-control study 19 Greek adolescents with Polycystic Ovary Syndrome (PCOS) and 21 non-PCOS controls were assessed for their hormonal, somatometric and autonomic nervous system profile in supine position. The study adhered to the Helsinki Guidelines of Good Clinical Practice. Significant differences were found only in very low frequencies (VLF) (P = 0.008) and Power spectral density RR (PSD) (P < 0.001) between adolescents with PCOS and controls. PSD was found decreased, a finding when combined with the VLF points to thermoregulatory delays. VLF is related to renin-angiotensin-activity, suggesting early onset of hormonal fluctuations and/or cardiometabolic manifestations related to the syndrome. The fact that no other autonomic nervous system or cardiac marker was disturbed, suggests that in this early stage no cardiovascular disease onset was detected. The finding suggests future research should focus on the role of cholinergic and vagal innervation to the development and persistence of the disease.
Article tools
My recent searches
My recently viewed abstracts
ESPE Abstracts
© Bioscientifica 2024 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more