ESPE2022 Poster Category 2 Pituitary, Neuroendocrinology and Puberty (35 abstracts)
Central precocious puberty in a girl with vasculitis-related moyamoya syndrome
Dandan Xie 1 , Qiuli Chen 2 , Huamei Ma 2 , Bo Jiang 2 , Yanhong Li 2 , Jun Zhang 2 , Song Guo 2 , Rujiang Zheng 2 & Zhixin Chen 2
1The First Affiliated Hospital, Sun Yat-sun University, Guangzhou, China; 2The First Affiliated Hospital, Sun Yat-sun University, guangzhou, China
Object: To raise the awareness of clinical manifestations about vasculitis-related moyamoya syndrome by summarizing the clinical characteristics of a girl with central precocious puberty, vasculitis-related moyamoya syndrome and reviewing the literature. Method: We carried on the review analysis to the patient with central precocious puberty, vasculitis-related moyamoya syndrome and reviewed the literature. Result: The bilateral breast development was the primary symptom in this patient at the age of 1 year and 6 months, and she was diagnosed as central precocious puberty. At the age of 3 years and 1-month, pituitary MRI, MRA, MRS, DWI and SWI were performed in our hospital to diagnose "vasculitis associated moyamoya syndrome"; Due to the poor control of bone age under the treatment of GnRHa, 17 OHP was found to be high, and the NCCAH was considered by adrenocorticotropic hormone provocation test. Conclusion: We reported a rare case of CPP with V-MMS for the first time in China. It is suggested that V-MMS can coexist with CPP and may be the etiology of the latter.
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