ESPE Abstracts

Marrow fat (BMAT) is an essential component of the bone marrow niche and plays a critical role during adaptive metabolism and stress responses. BMAT increases from birth and reaches a peak during adolescence and then is maintained until late in life when it increases again. Previous studies demonstrated a negative relationship between bone mineral density and BMAT; however those were predominantly cross sectional studies. New mouse models and inbred strains have provided novel...