ESPE Abstracts

Objective: To determine the frequency, clinical spectrum, and risk factors for microvascular complications in children and adolescent with T1DM.Methodology: Descriptive, observational study was conducted over 1 year (April 2023 till March 2024) at the Department of Pediatric Endocrinology and Diabetes, The Children's Hospital, Lahore, Pakistan. Total 127 patients, aged 1 to 18 years having minimum 3 years of T1DM in...

Background and Objective: Diabetic ketoacidosis (DKA) is an acute endocrinological emergency in childhood. It occurs in 20-40% of cases at the onset of Type 1 Diabetes (T1D). DKA is classified as mild, moderate, and severe based on the clinical picture and blood pH levels. This study aims to evaluate the relationship between the characteristics of T1D onset (DKA level, pH, c-peptide) and the glycometabolic control 2, 5, and 10 years after the diagnosis.<p ...

Background and Objective: Type 1 Diabetes (T1D) is one of the most frequent endocrine-metabolic diseases in children and youth. Several studies assessed Sleep Quality (SQ) in Children with Diabetes (CwD), yielding conflicting results. This study aims to test the hypothesis that the use of glucose sensors and insulin pumps in T1D is associated with better QOL and SQ in a group of CwD and their parents/caregiversSubjects and Method...

Background: Arterial hypertension (AH) in young patients with Type 1 Diabetes (T1D) occurs more often, and at younger age than in general population. A reduction of nighttime dip value is considered as an early marker of AH risk.The aim of this study: was to identify the association between AH, and abnormal nighttime dip and diabetes-related factors: duration time and glycemic controlMethod...

Background: The incidence of Type 2 Diabetes Mellitus (T2DM) among children is escalating at an alarming rate, presenting a significant public health concern. This increase is intrinsically linked to the obesity epidemic, with most children diagnosed with T2DM being overweight or obese. While the oral glucose tolerance test (OGTT) remains the gold standard for diagnosing T2DM (and the preceding dysglycaemia), its accessibility and practicality in community set...

Background: The prevalence of type 2 diabetes mellitus (T2DM) in children and young people (CYP) is increasing in the United Kingdom and worldwide. There is a lack of evidence of patient and parent opinions of the care provided in T2DM and how care should be tailored to meet their needs. The aim of this study was to analyse the Parent and Patient Reported Experience Measures (PREM) survey responses specifically from patients with T2DM and their families in ord...

Background: Despite the increasing incidence of type 2 diabetes mellitus (T2DM) in Children and Young People (CYP), and its associated morbidities and poor long-term prognosis, there remains uncertainty in its management. Dietary interventions have been shown to be effective in adults with T2DM but little is known about their effectiveness in CYP. The aim of this systematic review is to provide up to date evidence on the impact of dietary interventions in T2DM...

Background: Diabetic nephropathy (DN) is the leading contributor to high morbidity and mortality in patients with type 1 Diabetes (T1D). Abuminuria, the gold standard marker of renal damage in diabetic nephropathy, lacks the sensitivity to detect the earliest changes in renal function; as renal histopathological changes were reported to be found before the onset of albuminuriaAim of the work: To assess the diagnostic rol...