ESPE Abstracts

Precocious puberty is the early development of secondary sexual characteristics occurring before the age of 9 in males. It is a rare condition affecting male individuals with only 41 reported cases in the Philippine Pediatric Society (PPS) Registry since 2006 and the first case to be reported in Region I. This is a case of a 4-year-old male, diagnosed with central precocious puberty (CPP) who presented with tall stature and early secondary sexual characteristics manifested as enlarged penis and scrotum, pubic hair growth, thin facial hair, facial acne and a history of body odor at 2 years of age. Plain radiographic examination of left hand and wrist revealed bone age of about 10-11 years old. Hormonal profile revealed elevated follicle stimulating hormone (FSH), luteinizing Hormone (LH) and, testosterone in the pubertal range. Cranial Magnetic Resonance Imaging (MRI) showed lobulated non-enhancing mass in the region of the right hypothalamus, which is consistent with a hypothalamic hamartoma. Hence, he was referred to a multidisciplinary team with the plan to initiate GnRH analog treatment with close monitoring of pubertal progression.