hrp0098p2-73 | Diabetes and Insulin | ESPE2024

Neonatal Diabetes Due to Insulin Gene Mutation

Liv Çanga Betül , Karagöz Kıymet , Şeyma Eken Emine , Korkmaz Vural Meltem , Yağmur Baş Ahmet , Kurnaz Erdal , Keskin Melikşah , Aslı Bala Keziban , Kolkıran Abdulkerim , Sezer Abdullah , Savaş Erdeve Şenay

Introduction: Neonatal diabetes mellitus (NDM) is a rare monogenic disease associated with genetic defects in pancreatic beta cell number and/or function. It can be divided into two forms: transient neonatal diabetes mellitus (TNDM) and permanent neonatal diabetes mellitus (PNDM). TNDM is usually diagnosed within the first month after birth and usually regresses before the age of one year, but may reappear during adolescence. In contrast, PNDM is a lifelong di...