hrp0097fc3.5 | Fat, metabolism and obesity 1 | ESPE2023

Early corneal nerve loss in children with obesity and type 2 diabetes

Gad Hoda , Dauleh Hajar , Chirayath Shiga , Pasha Maheen , Haris Basma , Amin Rasha , Afyouni Houda , Petrovski Goran , Shehzad Saira , Khalifa Amel , Mohammed Ahmed Elwaseila , Mohamadsalih Ghassan , Campbell Judith , Jolkka Sari , Biglang-awa Roshirl , Cuatrona Erlinda , Inso Gina , Razon Gerald , A. Hendaus Mohamed , Elgassim Einas , N. Petropoulos Ioannis , Ponirakis Georgios , A. Malik Rayaz , Hussain Khalid

Background: Childhood obesity is highly prevalent in the MENA region and may be associated with sub-clinical neuropathy.Methods: Children with obesity with normal glucose tolerance (NGT), impaired glucose tolerance (IGT) and Type 2 diabetes Mellitus (T2DM) and healthy controls (HC) underwent body composition analysis, assessment of vibration perception threshold (VPT), monofilament sensitivity and corneal confocal micros...

hrp0092p1-43 | Fat, Metabolism and Obesity | ESPE2019

Association of Biomarkers of Endothelial Dysfunction with MicroRNAs Levels in Overweight and Obese Adolescentes

Huang Fengyang , Brianza-Padilla Malinalli , Bonilla-Jaime Herlinda , del-Río-Navarro Blanca Estela , Villafaña-Rauda Santiago , Romero-Nava Rodrigo , Sánchez-Muñoz Fausto

Background and Aims: MicroRNAs play important regulatory roles in cholesterol homeostasis and endothelial dysfunction. The aim of present study was to characterize the expression of miRNAs in overweight/obese adolescents and to identify the possible correlation with metabolic profile and inflammatory biomarkers.Methods: 79 overweight and obese adolescents aged 13.0±2.0 years and 28 normal weight adolescents aged 13....