hrp0092p1-419 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology (2) | ESPE2019

Premature Ovarian Insufficiency in Women after Treatment for Childhoodcancer is a Risk Factor for Metabolic Syndrome

Netterlid Axel , Mörse Helena , Giwercman Aleksander , Henic Emir , Erfurth Eva-Marie , Elfving Maria

Background: Childhood cancer survivors (CSS) are at risk for several late effects, among them increased risk of metabolic syndrome (MetS). We wanted to study if female hypogonadism was a risk factor for MetS.Method: This study included 167 female CCS, mean age 34.3 (19.3-57.8) years in the South region of Sweden and 164 matched controls, mean age 35.0 (19.3–58.0). The female CCS were diagnosed at mean age 8.9 (0.1-1...

hrp0082p3-d1-962 | Sex Development | ESPE2014

46,XY Female with Turner Syndrome, Crohn’s Disease and Low Level Mosaicism for Monosomy X

Tas Emir , Yatsenko Svetlana , Popovic Jadranka

Introduction: Turner syndrome (TS) is characterized by short stature and premature ovarian failure. Genetic component of TS patients with diagnosis of inflammatory bowel disease has not been largely studied.Case Report: A 94/12-year-old girl with history of Crohn’s disease was evaluated for short stature. Her disease was well controlled with medications, however she continued with linear growth failure. Medical history included...

hrp0095p1-546 | Pituitary, Neuroendocrinology and Puberty | ESPE2022

Change of menarcheal age in schoolgirls living in Istanbul over the last 12 years

Guran Tulay , Alir Fahriye , Taha Arslan Yusuf , Molla Giasim , Sahin Berk , Emir Sayar Mehmet , Atay Zeynep , Helvacioglu Didem , Gurpinar Tosun Busra , Haliloglu Belma , Turan Serap , Hidiroglu Seyhan , Bereket Abdullah

Background: Menarche is the endpoint of a complex sequence of maturational events but is the unique marker of female puberty. Timing of menarche is a strongly heritable trait. However, secular trends suggest that lifestyle and/or environmental factors are important.Objective: To assess the trend in age at menarche (AAM) in Istanbul over the last 12 years, and compare the patterns according to socioeconomic status (SES), ...