ESPE Abstracts

Type 1 Diabetes (T1DM) is a chronic metabolic disease characterized by hyperglycemia due to absolute insulin deficiency as a result of autoimmune damage of pancreatic β cells. In its treatment, insulin, medical nutrition therapy and exercise is recommended. Although it is known that exercise contributes to disease control, the mechanism of these effects has not been fully clarified. It is thought that myokines such as irisin and sestrin, can be effective by secreting with...

Introduct&idot;on: Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by damage to β cells in the pancreas. Neopterins and indolamine 2,3-dioxygenase (IDO) activity, which is shown by the ratio of kynurenine to tryptophan, can be used as an indicator in the regulation of cellular immunity. Oxidative stress produced by xanthine oxidoreductase has been shown to be associated with vascular endothelial dysfunction. It uses the conversion of p...

Introduction: Antithyroid Drugs (ATD) are generally preferred at the onset of treatment with no consensus on the duration of ATD (propylthiouracil, methymasole) treatment Graves disease in children.Objective: Examining the effectiveness of ATD treatment on children and adolescents and determining the risk factors of remission and relapse.Method: A total of 45 cases with ages varying between 1–18 years diagnosed with Graves dis...

Background: Mayer-Rokitansky-Kuster-Hauser syndrome (MRKH) is characterized by utero-vaginal atresia in patients with a normal female phenotype and 46, XX karyotype. Various anomalies may accompany MRKH. The number of cases with accompanying hyperandrogenemia is limited.Case presentation: We describe a combination of Mullerian agenesis and hyperandrogenemia (total testosterone level 0.85 ng/ml) in a patient presenting with primary amenorrhea and mild hir...

Introduction and Aim: Pubertal gynecomastia is the transient proliferation of glandular tissue in breasts of men without any endocrin pathology. Relatively higher levels of estrogen than plasma testosteron levels and imbalance between tissue estrogen and testosteron levels are considered to be important in pathogenesis. In this study it is aimed to determine the clinical and laboratory properties of our patients who were diagnosed as pubertal gynecomastia and compare with heal...

Introduction and aim: Metabolic bone disorders due to calsium and vitamin D deficiency are one of the most frequent extraintestinal symptoms in Celiac disease. In this study it is aimed to evaluate bone mineral density in patients with Celiac disease during diagnose and evaluate the factors related to bone mineral metabolism.Material and Method: The study included 43 children diagnosed as Celiac disease between December 2015 and December 2017. Clinical, ...

Introduction and aim: The education of the diabetic patients and their parents is an important phase of diabetic treatment. It is accepted in general that good control in diabetes is not possible without enough knowledge and experience about diabetes. In this study it is aimed to evaluate the relation between diabetic education levels of type 1 DM child/adolescent and parents and metabolic control.Material and method: The study included the patients and ...

Background: The risk of pancreatitis increases when triglyceride levels rise above 1 000 mg/dl. This requires particular attention in subjects with type 2 diabetes, which is accompanied by elevated triglyceride levels in one in every two patients. Apheresis, a treatment option in pancreatitis developing secondary to hypertriglyceridemia, is expensive and not available in every centre. Another option, heparin administration, may result in rebound hypertriglyceridaemia. Thirdly,...

Background: Graves’ disease is a rare autoimmune thyroid disease that characterized by hyperthyroidism, diffuse goitre and ophthalmopathy. It generally involved both lobes of the thyroid, unilateral involvement was rare.Case report: A 18 year old girl presented with weakness, alopecia, menstruel irregularity. In physical examination moist skin, increased pulse rate (116/min) and enlargement of the right lobe of the thyroid was determined. Her blood ...

Aim: This study aimed to investigate retrospectively the demographic, clinical and laboratory data of patients followed up for hypothyroidism and to determine the insidance of persistent hypothyroidism.Materials and Methods: A total of 209 patients with hypothyroidism were included retrospectively in this study. Demographic data, clinical features, laboratory results, thyroid volume, follow-up time, treatment drug were recorded. These patients were divid...