ESPE Abstracts

Aims: To assess trend in the prevalence of severe obesity in a national population-based sample of adolescents and to evaluate the association of severe obesity with major cardio-metabolic morbidities.Methods: Prevalence and severity of obesity was determined among 373,226 Israeli adolescents with abnormal BMI (≥85th percentile for age and sex) examined in an obligatory health assessment at mean age 17.3±0.5 years between 1967 and 2...

Background: The efficacy of growth hormone (GH) treatment in short, healthy children diagnosed with growth hormone deficiency (GHD) or those meeting the criteria of idiopathic short stature (ISS) suggest that an overlap exists between these two conditions. Although flawed and inconsistent, growth hormone stimulation tests (GHST) are the key diagnostic tool differentiating between GHD and ISS affecting clinical decisions such as treatment eligibility and dose.<...