hrp0089p3-p298 | Pituitary, Neuroendocrinology and Puberty P3 | ESPE2018

Distinct Presentations of McCune Albright Syndrome, Report of Two Cases

Yesiltepe Mutlu Gul , Kabataş Eryilmaz Sema , Ceylaner Serdar , Hatun Sukru

McCune-Albright Syndrome is a rare genetic disorder characterized by triad of polyostotic fibrous dysplasia of bone, precocious puberty and café au lait skin pigmentation. It is resulted from an activating mutation in the GNAS gene encoding the alpha subunitof stimulatory G protein. Here we present two cases with McCune Albright syndrome presenting with different clinical findings.Case 1: A 7-year and 6 month-old girl presented with breast ...