hrp0097ee1.1 | Section | ESPE2023

Solidarity and justice in the Dutch Coverage Lock Policy for Expensive Medicines - public Opinions and Stakeholder Perspectives

van Thiel Ghislaine , Scheijmans Féline , van der Pol Willem , van Delden Johannes , Zomers Margot , van der Graaf Rieke , Fadaei Sina , Onrust Marthe , van der Wal Roosmarijn

Background: Solidarity-based healthcare systems face significant challenges due to the rising costs of new and highly expensive medicines for cancer and rare diseases. The Dutch government introduced the Coverage Lock (CL) policy in 2015 to restrict access to reimbursement for such drugs. The CL has raised controversy around its ethical acceptability. Some claim the CL is necessary to secure solidarity while others have pointed out that its leads to unfair ine...

hrp0097t17 | Section | ESPE2023

Deterioration in polysomnographic evaluation after COVID-19 infection in patients with Prader-Willi-Syndrome

Braun Sina , Schulte Sandra , Laemmer Constanze , Gohlke Bettina

Background: Patients with Prader-Willi-Syndrome (PWS) seem to be a risk-group for COVID-19 infection, due to their syndrome associated clinical features of hyperphagia and obesity, risk for central hypoventilation and obstructive sleep apnoea. Yet, little is known about the severity of infections and the long-term consequences in these patients. Therefore, we studied auxologic parameters and sleep laboratory examinations in PWS patients before and after COVID-...

hrp0095p2-243 | Pituitary, Neuroendocrinology and Puberty | ESPE2022

Delayed puberty by anomalies hypo-gonadotropic hypogonadism, hyper-gonadotropic hypogonadism and puberty induction

Asmae Touzani , Douaa Abdallaoui , Yamna Kriouile , Zineb Imane , Abdellah Dami , Lhousaine Balouch , Ahmed Gaouzi

Introduction: Delayed puberty is defined as the absence of the development of sexual characteristics beyond the age of 14 for boys and 13 for girls. To better understand this pathology, we conducted a retrospective study over a period of 7 years; between 2013 and 2020, involving 11 patients with a delayed puberty, followed by a pediatric endocrinology consultation at the children’s hospital Ibn Sina in Rabat.Patients:</stro...

hrp0095p2-278 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2022

Delayed puberty by anomalies hypo-gonadotropic hypogonadism, hyper-gonadotropic hypogonadism and puberty induction

Touzani Asmae , Abdallaoui Douaa , Kriouile Yamna , Zineb Imane , Dami Abdellah , Balouch Lhousaine , Gaouzi Ahmed

Introduction: Delayed puberty is defined as the absence of the development of sexual characteristics beyond the age of 14 for boys and 13 for girls. To better understand this pathology, we conducted a retrospective study over a period of 7 years; between 2013 and 2020, involving 11 patients with a delayed puberty, followed by a pediatric endocrinology consultation at the children’s hospital Ibn Sina in Rabat.Patients:</stro...