hrp0082p2-d2-543 | Puberty and Neuroendocrinology (1) | ESPE2014

Time to Menarche After Completing GnRH Agonist in Girls with Central Precocious or Early Puberty

Kim Shin-Hee , Jung In-Ah , Cho Won Kyoung , Cho Kyoung Soon , Park So Hyun , Jung Min Ho , Suh Byoung Kyu

Background: Treatment goals for central precocious puberty (CPP) in girls include preventing short final height due to early epiphyseal closure, and avoiding premature onset of menarche.Objective and hypotheses: Our aim was to evaluate the timing of menarche and the associated factors among patients with idiopathic CPP or early-onset puberty (EP) who were treated with GnRH agonists (GnRHa).Method: We analyzed clinical and laborator...

hrp0082p3-d2-741 | Diabetes (3) | ESPE2014

Incidence of Dyslipidemia and its Association with Glycemic Control in Adolescents and Young Adults with Type 1 Diabetes

Kim Shin-Hee , Jung In-Ah , Cho Won Kyoung , Cho Kyoung Soon , Park So Hyun , Jung Min Ho , Suh Byoung Kyu

Background: Hyperglycemia and dyslipidemia are metabolic abnormalities commonly found in type 1 diabetes.Objective and hypotheses: Limited data are available on the relationship between glycemic control and dyslipidemia in patients with type 1 diabetes. We aimed to investigate the incidence of dyslipidemia and its association with glycemic control in adolescents and young adults with type 1 diabetes.Method: This cross-sectional stu...

hrp0084p2-375 | Fat | ESPE2015

The Relation of Serum Nesfatin-1 Level with Anthropometric and Metabolic Parameters in Korean Children and Young Adolescents

Kim Shin-Hee , Ahn Moonbae , Jung In-Ah , Jeon Yeon Jin , Cho Won Kyoung , Cho Kyoung Soon , Park So Hyun , Jung Min Ho , Suh Byoung-Kyu

Background: Nesfatin-1, a recently discovered anorexigenic neuropeptide, seems to play an important role in hypothalamic pathways regulating food intake and energy homeostasis.Objective and hypotheses: The aim of this study is to evaluate the relation of serum nesfatin-1 level with anthropometric and metabolic parameters in children and adolescents.Method: This study included 78 Korean children and adolescents (42 obese/overweight ...

hrp0092p3-174 | Growth and Syndromes (to include Turner Syndrome) | ESPE2019

Population Prevalence of Down's Syndrome and Cardiac Complications in South Korea: Based on National Health Insurance Service (NHIS)

Lee Na yeong , Cho Won Kyoung , Suh Byun-Kyu

Backgrounds: There is a no reliable population-based prevalence data of Down's syndrome (DS) in South Korea. In the present study, we try to estimate the incidence and prevalence of DS and cardiac complications in South Korea using data of National Health Insurance Service (NHIS) data and Rare Diseases Registry.Methods: We collected the data on DS patients who registered in the Rare Diseases Registry (RDR) between 20...

hrp0092p2-166 | GH and IGFs | ESPE2019

Prediction of the First-Year Response to Growth Hormone Treatment in Prepubertal Korean Children with Idiopathic Growth Hormone Deficiency: Analysis of Data from the LG Growth Study Database

Cho Wonkyoung , Ahn Moon-Bae , Cho Kyoung Soon , Jung Min Ho , Suh Byung-Kyu

Background: Insufficient data exist for the prediction of the first-year response to growth hormone (GH) treatment in Korean prepubertal children with idiopathic GH deficiency (GHD).Methods: Data from children (n = 345) who were in the LG Growth Study Database or had participated in other relevant clinical trials were used to develop a model. All included patients had been diagnosed with idiopathic GHD with maximum G...

hrp0084p2-563 | Thyroid | ESPE2015

Nonautoimmune Neonatal Hyperthyroidism due to A633G Mutation in the Thyrotropin Receptor Gene

Jung In Ah , Cho Won Kyoung , Jeon Yeon Jin , Chae Hyo Jin , Kim Myung Shin , Suh Byung Kyu

Background: Congenital hyperthyroidism is a rare disease. In most patients with congenital hyperthyroidism are autoimmune forms caused by maternal thyroid-stimulating antibodies. In contrast to autoimmune hyperthyroidism that is transient, nonautoimmune form of congenital hyperthyroidism is persistent and results from activating germline mutations in the thyrotropin receptor (TSHR) gene.Case presentation: We report the case of a Korean male infant with s...

hrp0094p1-52 | Bone B | ESPE2021

Impact of Vertebral Fracture on Auxological Profile and Insulin-like Growth Factors of Children after Acute Lymphoblastic Leukemia Treatment

Bae Ahn Moon , Kim Sung Eun , Lee Na Yeong , Ki Kim Seul , Hee Kim Shin , Kyoung Cho Won , Soon Cho Kyoung , Ho Jung Min , Suh Byung-Kyu ,

Purpose: To investigate the overall prevalence of vertebral fractures (VF) following childhood acute lymphoblastic leukemia (ALL) treatment and examine the association of VF with growth trajectory and insulin-like growth factorsMethods: Children (n = 172; 59.3 % male) diagnosed with ALL at age between 2 and 18 years were assessed for VF by screening the lateral thoracolumbar spine radiographs (Genant’s semi-quantitative met...

hrp0092p2-85 | Diabetes and Insulin | ESPE2019

Clinical Characteristics and Treatment Outcomes in Patients with Autoantibody-negative Ketosis-prone Diabetes

Kim Shin-Hee , Ahn Moon-Bae , Kim Seulki , Choi Yujung , Lee Seonhwa , Cho Won Kyoung , Cho Kyoung Soon , Jung Min Ho , Kyu Suh Byung

Objective: Ketosis-prone diabetes (KPD), characterized by presentation with diabetic ketoacidosis (DKA) in patients lacking the typical features of autoimmune type 1 diabetes, is a heterogeneous syndrome. The objective of this study is to ascertain the presence of A-β+ (autoantibody-negative, β-cell functional reserve) KPD in Korean children and adolescents and to study their characteristics in this group. Method: Diabetes ...

hrp0089p2-p026 | Adrenals and HPA Axis P2 | ESPE2018

Early Recognition of Adrenal Insufficiency after Hematopoietic Stem Cell Transplantation During Childhood

Choi Yujung , Lee Seonhwa , ki Kim Seul , Lee Eun Kyoung , Shin Jung-Hyun , Ahn Moon Bae , Cho Won-Kyoung , Jung Min-Ho , Suh Byung-Kyu

Purpose: We try to analyze the prediction capacity of variable factors to diagnose adrenal insufficiency.Methods: We analyzed clinical and laboratory data of 22 children (Male =13) who have been checked regular dose ACTH stimulation test for suspected symptoms after HSCT (Lymphoid leukemia=5, Myeloid leukemia=9, Non-malignant=8) at the Catholic HSCT center from Feb 2013 to Feb 2017 at Seoul St. Mary’s Hospital. A normal response of ACTH stimulation ...

hrp0086p1-p135 | Bone & Mineral Metabolism P1 | ESPE2016

Low Bone Mineral Density in Adolescents with Leukemia After Hematopoietic Stem Cell Transplantation

Kyoung Cho Won , Bae Ahn Moon , Hee Kim Shin , Soon Cho Kyoung , Hyun Park So , Ho Jung Min , Suh Byung-Kyu

Background: Hematopoietic stem cell transplantation (HSCT) has improved the prognosis of children with malignant hematologic disease. However, it has had significant adverse effects on the endocrine system, including bone health. Limited studies are available to assess osteoporosis in survivors of adolescents after HSCT.Objective and hypotheses: We investigate the bone mineral density (BMD) and endocrinopathy/treatment factors associated with low BMD in ...