hrp0089p1-p244 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology P1 | ESPE2018

Polycystic Ovarian Syndrome in Adolescents: Characterising the Clinical Phenotype and the Role of Precision Medicine

Gunn Harriet , Agarwalla Vathsala , Skinner Rachel , Milne Bronwyn , Mills Kevin , Steinbeck Katharine

Background: Polycystic ovarian syndrome (PCOS) is the most common hormone disorder in adolescent and young adult females, affecting 4–20% of the population. PCOS is associated with metabolic dysfunction, pro-inflammatory processes and mood disorders. Despite this, it is poorly understood in younger adolescents, and diagnosis and management remain challenging.Objectives: To better understand the clinical phenotype of PCOS in adolescents. Subsequently...

hrp0089p3-p165 | Fat, Metabolism and Obesity P3 | ESPE2018

Hidden Hunger in Overweight/obese Indian Adolescents

Jain Vandana , Upadhyaya Babita , Agarwala Anuja

Background and Objective: Overweight/obese children may have unrecognized deficiency of several essential micronutrients owing to their faulty dietary habits. These may impair their physical and mental development. Deficiency of specific minerals and vitamins that co-factors in metabolic and signalling pathways, such as choline, zinc, magnesium, vitamins D and B12 may also predispose to insulin resistance, fatty liver and metabolic syndrome. This study was undertaken to assess...