ESPE Abstracts

Background: Patients with genetic variants in the melanocortin-4 receptor (MC4R) pathway may present with early-onset, severe obesity and hyperphagia. Increasing awareness of genetic testing could improve diagnosis of rare genetic causes of obesity and identify patients who might benefit from targeted therapy; however, such testing has been limited. Moreover, the frequency of specific genetic variants in this population is currently unknown. The Rare Obesity A...

Introduction: Mental health comorbidities are getting more recognized in children with chronic illness like Type 1 Diabetes Mellitus (T1DM). Increased rates of depressive symptoms and anxiety dis¬orders in pediatric patients with TIDM have been found in many previous studies. However, not much literature is available regarding impact of multidisciplinary intervention in pediatric patients with T1DM in developing countries where there is increased patient l...