hrp0089p1-p212 | Pituitary, Neuroendocrinology and Puberty P1 | ESPE2018
Juliusson Petur Benedikt
, Dahlgren Jovanna
, Abuzzahab M Jennifer
, Pedersen Birgitte Tonnes
, Roehrich Sebastian
, Romano Alicia
Objectives: Current safety data do not indicate an association of GH therapy with increased risk for development/progression of tumours, or worsening of congenital cardiac conditions in individuals with Noonan syndrome (NS); however, data are limited. This report describes real-world safety data on GH therapy in paediatric patients with NS.Methods: Two complementary non-interventional, multicentre studies, NordiNet IOS (NCT00960128) and ANSWER Program (N...