hrp0086fc10.6 | Perinatal Endocrinology | ESPE2016

Developmental Programming of Somatic Growth, Behavior and the Endocannabinoid System (ECS) by Variation of Early Postnatal Nutrition in a Cross-Fostering Mouse Model

Schreiner Felix , Ackermann Merle , Michalik Michael , Rother Eva , Bilkei-Gorzo Andras , Racz Ildiko , Dotsch Jorg , Zimmer Andreas , Woelfle Joachim

Background: Nutrient deprivation during early development has been associated with the predisposition to metabolic disorders in numerous epidemiological studies. Experiments with rodents also indicate a developmental plasticity of neuropsychological characteristics following alterations of early postnatal nutrition.Objective: Considering its interaction with metabolism and regulation of appetite and behavior, the endocannabinoid system (ECS) may represen...