ESPE Abstracts

Background: The morphological and biochemical phenotype of Paired Box Domain Gene PAX8 mutation in patients with congenital hypothyroidism (CH) is variable. The contribution of mutations in PAX8 gene in children with CH and dysgenetic or orthotopic thyroid glands still remains a subject of interest of researchers.Objective and hypotheses: This study presents mutational analysis of the PAX8 gene in patients with primary CH.Method: 5...

Aim: To identify factors affecting compliance to treatment with recombinant growth hormone (rhGH) in children with growth hormone deficiency (GHD).Study population and Methods: The following data were collected during standard visits in 8 endocrine clinics in Poland: medical history, auxological measurements, laboratory tests and the numbers of empty and full rhGH ampoules dispensed and returned by the patients. The obse...

Objective: The aim of this study was to assess the compliance with recombinant growth hormone (rhGH) therapy in children diagnosed with growth hormone deficiency (GHD) and identify the factors that may influence compliance.Study Population and Methods: This multicentre study was conducted in 12 endocrine clinics in Poland. During routine visits, medical history, auxological measurements, laboratory tests, and the quantit...