hrp0086fc3.6 | Pituitary | ESPE2016
Thomas-Teinturier Cecile
, Simonin Gilbert
, Vaczlavik Anna
, Ajaltouni Zaina
, Gaillard Stephan
, Bougneres Pierre
, Chanson Philippe
Background: We describe our experience in medical therapy for invasive somatotroph pituitary macroadenomas in 8 children or adolescents presenting with acromegaly/gigantism, in terms of growth and IGF-I levels control.Patients: Eight children, aged 5 to 17 years (median 12.4 years), presented with growth hormone (GH) hypersecretion related to somatotroph pituitary macroadenomas with cavernous sinus invasion in 6/8. Genetic testing revealed AIP mutation i...