hrp0092p3-203 | Pituitary, Neuroendocrinology and Puberty | ESPE2019

Anapylaxis Secondary to Gonadotrophin Releasing Hormone Agonist used for Precocious Puberty, Two Case Reports

Al Shaikh Hala

Gonadotrophin Releasing Hormone agonists (GnRHa) are used in the management of true precocious and early onset puberty. They have been associated rarely with severe adverse effects such as slipped capital femoral epiphysis, sterile abscess formationand anaphylaxis. Anaphylactic reactions had been reported at a low incidence rate. They can occur early or late after starting treatment or be recurrent after an injection due to the analogue's long half-life.The allergic reacti...