hrp0098p1-288 | Thyroid 3 | ESPE2024

Assessment of regulatory B cells in peripheral blood and zinc transporter 8 expression in thyroid tissue in children with autoimmune thyroid diseases

Stożek Karolina , Starosz Aleksandra , Opęchowska Aleksandra , Bossowski Filip , Moniuszko Marcin , Grubczak Kamil , Bossowski Artur

Introduction: There has been a growing trend in the incidence of autoimmune thyroid diseases (ATD) in the pediatric group of patients. The new aspects of its pathogenesis may contribute to understand innovative methods of prevention and treatment. Regulatory B cells (Breg) allow the maintenance of immune homeostasis by neutralizing the negative reactions of effector cells. Attention has been recently paid also to the new environmental factor like zinc and its ...