hrp0082p3-d2-723 | Diabetes (1) | ESPE2014

Estimation of Compensation and Prevalence of Chronic Complications of Type 1 DM in Children According to the Screening Data

Alimova Nasiba , Rakhimova Gulnara

Objective and hypotheses: The work was initiated to comparatively assess degree of compensation and prevalence of complications of type 1 DM in children in Uzbekistan from 1998 to 2012 according to the screening data.Method: 950 children (coverage of 80.3%) with type 1 DM were screened in 2012 within the WDF grant ‘Children’s Diabetes in Uzbekistan’, the degree of compensation and prevalence of type 1 DM chronic complications were compared...

hrp0084p3-708 | Diabetes | ESPE2015

Incidence and Risk Factors of Diabetic Nephropathy in Children and Adolescents as Per Republic of Uzbekistan National Register

Rakhimova Gulnara , Alimova Nasiba

Aim: To study incidence and risk factors of diabetic nephropathy (DN) in children and adolescents as per the Republic of Uzbekistan National Register.Method: An information list (card) and appropriate software were developed on the basis of the DN register. The cards were collected in every region of Uzbekistan to be introduced into a computer database.Results: DN screening performed in children by Alikhanova N M in 1998 showed tha...

hrp0092p3-49 | Diabetes and Insulin | ESPE2019

Significance of the Early Marker of Nephrine Diabetic Nephropathy of the Uzbek Nationality with the First Type of Diabetes Mellitus

Rakhimberdiyeva Ziyoda , Shagazatova Barno , Alimova Nasiba

Goal of Research: to assess the significance of the early marker of nephrine diabetic nephropathy of the Uzbek patients with the First Type of diabetes mellitus.Materials and Methods: 100 patients with DM 1 were examined, including 80 patients with normoalbuminuria (NAU) and 20 patients at the microalbuminuria (MAU). The patients were from 1 to 14 years old with the disease duration from 1 to 5 years. They included 48 bo...

hrp0084p2-288 | Diabetes | ESPE2015

Functional Condition of the Kidneys (K/DOQI, 2002) by ACE Gene I/D Polymorphism in Children and Adolescents with Type 1 Diabetes Mellitus

Rakhimova Gulnara , Sadikova Akida , Alimova Nasiba

Aim: The work was initiated to assess functional condition of the kidneys and to study interrelation between ACE gene I/D polymorphism and stage of chronic kidney disease in children and adolescents with type 1 diabetes mellitus (DM) in compliance with K/DOQI recommendations (2002).Materials and methods: We examined 120 children and adolescents with type 1 DM, 53 (44.2%) males and 67 (55.8%) females among them (mean age 13.8±0.24 years; 95% CI: 13.3...

hrp0092p2-104 | Diabetes and Insulin | ESPE2019

Insulin Pump Therapy Implementation in Uzbekistan

Hanmehmet Khilola , Ibragimovich Ismailov Said , Usmanovna Alimova Nasiba

Background: Devices for continuous subcutaneous insulin infusion have become fundamentally new and progressive step in the treatment of diabetes.Aims and objectives: To evaluate the effectiveness of insulin pump therapy in comparison with the regime of multiple daily injections (MDI) of insulin.Materials and Methods: Forty children and adolescents with type 1 diabetes from 5 to 17 ...

hrp0084p3-749 | Diabetes | ESPE2015

Achievement of Therapy Targets in Children and Adolescents with Type 1 Diabetes Mellitus at the “Diabetes School”

Rakhimova Gulnora , Ismailov Said , Tashmanova Akmaral , Alimova Nasiba

Objective and hypotheses: The work was initiated to assess efficacy of training and achievement of therapy targets in children and adolescents with type 1 diabetes mellitus in “Diabetes Schools”.Method: The five-day training course was conducted in “Type 1 Diabetes School” at the Center for the Scientific and Clinical Study of Endocrinology, Uzbekistan Public Health Ministry (Tashkent). The training was conducted by means of a structu...

hrp0095p2-78 | Diabetes and Insulin | ESPE2022

Complications of Covid-19 on the thyroid gland functioning

Ismailov Said , Alimova Nasiba , Jumaeva Hilola , Nasirova Khurshida

Annotation: Pandemics of coronoviral infection continues affecting the wold community, and with the comprehension of its pathological physiology an interest in endocrine effects ofSARS-CoV-2 grows too. It was determined, that the main target organs affected by SARS-CoV-2 were lungs and immune system, while it is still not clear if SARS-CoV-2 has any impact on the thyroid function. In patients infected with SARS-CoV, coronovirus relevant to SARS-CoV-2, damage o...

hrp0092p1-325 | Diabetes and Insulin (2) | ESPE2019

Association of CTLA-4 Gene with the Familial Diabetes Mellitus

Saatov Talat , Karimov Khamid , Rakhimova Gulnora , Ibragimov Zafar , Ibragimova Elvira , Ishankgodjaev Tokhir , Alimova Nasiba , Abduvaliev Anvar , Shamansurova Zulaykho

The work was initiated to study role of CTLA4 gene in the onset of familial diabetes mellitus. The samples of peripheral blood taken from children (mean age 12.5 years) of patients with type 1 diabetes mellitus and their blood relatives, such as parents and siblings, and apparently healthy subjects were used in the study. Among the recruits, there were 56.5% of boys and 43.5% of girls. The findings from the genotyping of CTLA4 gene 49A/G polymorphism demonstrated no si...