hrp0086p2-p497 | Fat Metabolism and Obesity P2 | ESPE2016

Cardiometabolic Effect of Sugar-Sweetened Beverages Reduction in Obese Children

Galhardo Julia , Diamantino Catarina , Alonso Anabela , Lopes Lurdes

Background: The excessive consumption of sucrose, primarily used in sweetened beverages, has been considered an important inducer of cardiometabolic diseases. Besides the association between metabolic syndrome and fructose found in animal models, literature is lacking prospective studies in humans, especially in paediatric ages.Objective and hypotheses: We assessed the effect of sugar-sweetened beverages reduction on markers of metabolic syndrome in obes...

hrp0084p1-31 | Diabetes | ESPE2015

Type 1 Diabetes Onset: A Story of Innate and Adaptive Immune Cells?

Fitas Ana Laura , Martins Catarina , Alonso Anabela , Nunes Gloria , Pina Rosa , Amaral Daniela , Lenzen Sigurd , Lopes Lurdes , Borrego Luis Miguel , Limbert Catarina

Background: Type 1 diabetes (T1D) is a T cell-mediated autoimmune disease. A more complex immunological picture is being unraveled, with a key role of innate immune cells at disease onset and maintenance. For new therapies based on immune-modulation to be possible, immune characterization of T1D patients is crucial.Objective and hypotheses: We aimed to characterise innate and adaptive immune cells of T1D children at a well-defined ‘onset-window&#146...