ESPE Abstracts

Key words: primary hyperparathyroidism, parathyroid gland, genetic study.Background: Primary hyperparathyroidism (PHPT) is a rare disease with a prevalence up to 2-5:100,000. About 90-95% of cases are isolated adenomas, 5-10% cases are due to hereditary syndromes. Parathyroid carcinomas occur in less than 1%.Aim: To study clinical features and genetic characteristics of patients wi...

Introduction: Parathyroid carcinoma (PC) is a malignant neoplasm and occurs in patients with primary hyperparathyroidism (PHPT) in less than 1% of cases. There are few descriptions of PC in children in the literature. Clinical manifestations of PHPT in children are highly variable: the disease may present with dyspeptic manifestations, symptoms of intoxication, bone deformities, urolithiasis, cholelithiasis or be asymptomatic.Mat...