ESPE Abstracts

Introduction: Klinefelter syndrome (KS) is the most common sex-chromosome disorder and cause of infertility and hypogonadism in males. However, KS remains an underdiagnosed condition with the majority of expected cases escaping clinical diagnosis and follow-up. Generally, the mid-puberty endocrine profile associated with KS is characterized by elevated levels of gonadotropins due to diminished testosterone feedback.Objective:</st...

Background: Recent research has demonstrated earlier testicular and pubertal development in Western boys. New ultrasound-based references of testicular growth in Norwegian boys are now available. Population specific references for FSH, LH and sex steroid hormones have not been previously available in Norwegian children and adolescents.Objective and hypotheses: We aimed to provide an elaborate description of pubertal development in a sample of contemporar...