hrp0098p2-393 | Late Breaking | ESPE2024
Cross Heather
, Peckham Hannah
, Peng Junjie
, Radziszewska Ania
, Butler Gary
, Jury Elizabeth
, Rosser Elizabeth
, A Robinson George
, Ciurtin Coziana
Introduction: Sex differences associated with inflammation have been observed across numerous autoimmune and cardiometabolic conditions. We aim ed to explore the differential impact of sex hormones/sex chromosomes on molecular pathways potentially relevant for immune cell functions using a unique post-pubertal transgender cohort.Methods: RNA-sequencing was performed on peripheral blood mononuclear cells (PBMCs) from a he...