hrp0086p1-p46 | Adrenal P1 | ESPE2016
Stefa Alketa
, Lamprokostopoulou Agaristi
, Kontogeorgou Anna
, Briana Despina
, Malamitsi-Puchner Ariadne
, Tsitsilonis Ourania
, Gagos Sarantis
, Charmandari Evangelia
Background: Telomeres are specialized nucleoprotein structures located at the ends of chromosomes playing a crucial role in genomic stability. They consist of tandem repeats of the noncoding hexameric TTAGGG sequence. Telomere shortening has been associated with cardiovascular disease, hypertension, type 2 diabetes, atherosclerosis, coronary heart disease and stroke, and has been proposed as a biomarker for ageing and a prognostic factor for age-associated diseases.<p clas...