hrp0098p1-229 | Diabetes and Insulin 4 | ESPE2024

Nighttime Blood Pressure Disturbances in Children with Long-Term Type 1 Diabetes

Stepniewska Anna , Szczudlik Ewa , Drozdz Dorota , Wojcik Malgorzata , Nazim Joanna , Janus Dominika , Starzyk Jerzy

Background: Arterial hypertension (AH) in young patients with Type 1 Diabetes (T1D) occurs more often, and at younger age than in general population. A reduction of nighttime dip value is considered as an early marker of AH risk.The aim of this study: was to identify the association between AH, and abnormal nighttime dip and diabetes-related factors: duration time and glycemic controlMethod...

hrp0098p3-307 | Late Breaking | ESPE2024

Disorders of the Melanocortin Pathway: From Genetic Inheritance to Clinical Manifestations Based on a Family Case Study

Stepniewska Anna , Szczudlik Ewa , Preizner-Rzucidło Ewelina , Wójcik MAłgorzata , B. Starzyk Jerzy

It is estimated that single-gene mutations are responsible for 3-10% of childhood obesity cases. The most common of these is a mutation in the MC4R gene, occurring in about 1-6% of children and 1% of adults with early-onset severe obesity. We report on of 7-year-old male twins with severe obesity (86% and 75% excess body mass relative to height), starting from the second year of life, along with hyperphagia. The boys were born from a twin pregnancy, PIII, CC, at 37 weeks of ge...